June 16, 2020

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

 

Attn:    Ms. Tracey McKoy

Ms. Kate Tillan

Mr. Tim Buchmiller

Ms. Celeste Murphy

 

Re:	Repare Therapeutics Inc.

Registration Statement on Form S-1

Registration No. 333-238822

 

Acceleration Request

Requested Date: June 18, 2020

Requested Time: 4:00 PM, Eastern Daylight Time

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended (the “Act”), Morgan Stanley & Co. LLC, Goldman Sachs & Co. LLC, Cowen and Company, LLC and Piper Sandler & Co., as representatives of the several underwriters, hereby join Repare Therapeutics Inc. in requesting that the Securities and Exchange Commission (the “Commission”) take appropriate action to cause the Registration Statement on Form S-1 (File No. 333-238822) (the “Registration Statement”) to become effective on June 18, 2020, at 4:00 PM, Eastern Daylight Time, or as soon as practicable thereafter.

Pursuant to Rule 460 under the Act, please be advised that we will take reasonable steps to secure adequate distribution of the preliminary prospectus, to underwriters, dealers, institutions and others, prior to the requested effective time of the Registration Statement.

We have been informed by the participating underwriters that they will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended, to the extent applicable.

[Signature Page Follows]

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cc:	Lloyd M. Segal, Repare Therapeutics Inc.

Mitchell S. Bloom, Goodwin Procter LLP

Seo Salimi, Goodwin Procter LLP

Divakar Gupta, Cooley LLP

Ryan S. Sansom, Cooley LLP

Marc A. Recht, Cooley LLP

Courtney T. Thorne, Cooley LLP

[Signature Page to Acceleration Request]